From CSBLwiki
Mode of actions
- (Fungus) "The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the dissaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose."[1]
Accessibility
Endoglucanse
- e.g. T. reesei EG-1; GH7; CBM1
Exoglucanase
- Reducing end acting exoglucanase (CBH I) from T. reesei; GH7; CBM1
- Non-reducing end acting (CBH II); GH6; CBM1
Mixed
Processivity
Synergism
Error fetching PMID 7980450:
- Error fetching PMID 7980450: [Synergism1]
Substrates
Crystalline cellulose
Non-crystalline cellulose
etc.
CAZy GH families
CAZy class | Taxonomic distribution | Gene name | Mode | Clan | Typical organisms
|
GH5 | A,B,E | Cellulase family A | | GH-A | Saccharophagus,Clostridium
|
GH6 | B,E | CBH-II, Cellulase family B | non-reducing end(exo) | | Chrysosporium,Trichoderma,Saccharophagus
|
GH7 | E | EG-I, CBH-I, Cellulase family C | reducing end(exo) | GH-B |
|
GH8 | B | Cellulase family D | Endo-, Exo- | GH-D |
|
GH9 | A,B,E | Cellulase family E | Endo- | |
|
GH44 | B(E) | Cellulase family J | Endo- | | Clostridium
|
GH48 | B,E | | Endo- | | Clostridium,Hahella
|