Research topics

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	===Protein-Protein Interactions===		===Protein-Protein Interactions===
	===[[human disease network|Human Disease Network]]===		===[[human disease network|Human Disease Network]]===
-	*UMLS
-	**Brief introduction (2006) ([[media:umlsintro.pdf|PDF]])
-	**UMLS Metathesaurus [http://www.nlm.nih.gov/research/umls/metab.html#sb_0 Columns & Data elements]
	*references		*references
	#What is a scale-free network? [[media:sciam.2003.scalefree.pdf|Sci. Am. (2003) Barabasi]]		#What is a scale-free network? [[media:sciam.2003.scalefree.pdf|Sci. Am. (2003) Barabasi]]
	#What is network biology? [[media:nrg.2004.networkbiology.pdf|Nat. Rev. Genet.(2005) Barabasi]]		#What is network biology? [[media:nrg.2004.networkbiology.pdf|Nat. Rev. Genet.(2005) Barabasi]]

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Revision as of 02:39, 18 February 2011

Contents 1 Evolutionary perspective 2 Synthetic Biology 2.1 iGEM 2010 2.2 iGEM 2009 2.3 Protein Engineering 2.4 Bioenergy 2.5 Metabolic Engineering 3 Genome Sequencing 3.1 Project#1 3.2 Project#2 3.3 softwares 4 Network biology 4.1 Protein-Protein Interactions 4.2 Human Disease Network

Evolutionary perspective

• Nothing in biology makes sense except in the light of evolution - T. Dobzhansky
• SNP analysis & Molecular population genetics
• Phylogenomics (comparative genomics)
• Evolution of protein domain families
  • Horizontal Gene Transfer (HGT)

Synthetic Biology

iGEM 2010

• Team - Korea_U_Seoul

iGEM 2009

• Team - KU_Seoul
  

  

  KU_Seoul

Protein Engineering

• aryl acylamidase

Bioenergy

• Exploring the CAZy: we are developing new CBM (Carbohydrate Binding Modules) classification system: 3D-Map
• CArbohydrate Related Domain database - CARD DB
  • Protein Domains for Biomass Deconstruction - PDBD DB

• Biomass deconstruction
  • Land biomass
  • Marine biomass
    • Agar
  • Related Enzymes
  • Related Microbes

Metabolic Engineering

• Cellulose utilization

Genome Sequencing

Project#1

• Status

Project#2

• Status

softwares

• Conversion among formats fa_all2std.pl

Network biology

Protein-Protein Interactions

Human Disease Network

• references

1. What is a scale-free network? Sci. Am. (2003) Barabasi
2. What is network biology? Nat. Rev. Genet.(2005) Barabasi