Structural phylogeny
From CSBLwiki
Contents |
Concept
- Protein structures (3D) were parsed into a finite number of structural alphabets
- Using these structural alphabets, identify meaning structural words..
- Frequent structural words (motifs?) and popular sentences (super secondary structures?)
- Using words to relate molecules (proteins) and organismic phylogeny (genomes; book)
Procedure
Standard data set
- We are going to use the SCOP DB: sequences and structures in the Astral compendium
Torsion angles
- Structural alphabets based on torsion angle distributions in the ramachandran plot
images to be posted...
Calculation
- Following tools can be used to calculate torsion angles of backbones
